Clinical research brings cutting-edge treatments to CHKD patients years before they are available to the public.
provides a setting for many clinical research trials. Highlights of the basic
science research include protection of the newborn brain from the effects of
hypoxic injury, new innovations to combat serious invasive infection,
management of autism, and emergency interventions for asthma.
research includes new medications and other therapies, clinical outcomes
analyses and epidemiological studies sanctioned by the Eastern Virginia Medical
School Institutional Review Board. There were 182 IRB-approved active funded studies in FY15. Topics of study
included hematology/oncology, allergy/asthma, infectious disease, neurology,
pediatric surgery, cardiology, otolaryngology, pulmonology, gastroenterology,
child abuse, endocrinology, dermatology, neonatology and mental health.
these studies are stage-three clinical trials that bring cutting-edge
treatments to CHKD patients years before they are available to the public. In addition, there is an increased focus on registry
studies across all disciplines. Data collected in these registries is
intended to standardize optimal levels of care and lead to improved patient
Our Division of Community Health
and Research has focused on conditions and issues impacting children’s health
with an emphasis on health disparities in the cities of the Hampton Roads
region, western Tidewater, and the rural Eastern Shore. Current areas of
emphasis include childhood obesity, asthma, e-cigarette
use by adolescents and young adults, teen pregnancy, infant and child passenger safety, and teen alcohol and other
CHKD is also a member of Children's Oncology Group (COG), an international research group that conducts clinical trials for children with cancer.
As a member, CHKD has access to the latest protocols for treatment of
childhood cancer, providing the community and region with the best
practices and treatment results from more than 240 COG-member hospitals
in North America, Australia, New Zealand, and Europe.
In FY15, CHKD had 93 COG studies including LTF studies open to
enrollment or undergoing data analysis. Several of these studies were
included in COG’s long-term follow-up study, which collects data on
patients who have participated in studies that are no longer open to
In all, approximately 200 CHKD patients participated in either open or follow-up COG studies in FY15.