Dr. Kenji Cunnion

(757) 668-7238

Practice
Board Certifications

American Board of Pediatrics

Pediatric Infectious Disease

Education

Medical School: Duke University

Residency: Medical College of Virginia

Fellowship: Duke University

Bio
Dr. Cunnion completed research and clinical fellowships in the area of pediatric infectious disease at Duke University. He currently serves as an associate professor of pediatrics and an associate professor of microbiology and molecular cell biology at EVMS.
Clinical interests
  • HIV
  • Staphylococcus aureus disease
  • Infections in immunocompromised patients
Honors & awards
Hampton Roads Magazine "Top Docs" 2013
Research
  • Staphylococcus aureus interactions with the complement immune system
  • Hyperglycemia effects on complement, innate immunity in cystic fibrosis
  • Development of a novel anti-inflammatory complement inhibitory peptide - PIC1
Publications

Selected from 30 peer-reviewed publications:

  • Mauriello CT, Pallera HK, Sharp JA, Woltmann JL Jr, Qian S, Hair PS, van der Pol P, van Kooten C, Thielens NM, Lattanzio FA, Cunnion KM, Krishna NK. A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility. Molecular Immunology. 53(1-2):132-9. 2013 Jan.
  • Hair PS, Echague CG, Rohn RD, Krishna NK, Nyalwidhe JO, Cunnion KM. Hyperglycemic conditions inhibit C3-mediated immunologic control of staphylococcus aureus. Journal of Translational Medicine. 10(1):35. 2012 Mar.
  • Sharp JA, Echague CG, Hair PS, Ward MD, Nyalwidhe JO, Geoghegan JA, Foster TJ, Cunnion KM. Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic. PLoS ONE 7(5): e38407. 2012 June.
  • Hair PS, Wagner SM, Friederich PT, Drake RR, Nyalwidhe JO, Cunnion KM. Complement regulator C4BP binds to staphylococcus aureus and decreases opsonization. Molecular Immunology. 50(4):253-61, 2012 Apr.
  • Sharp JA, Cunnion KM. Disruption of the alternative pathway convertase occurs at the staphylococcal surface via the acquisition of factor H by staphylococcus aureus. Molecular Immunology. 48(4): 683-690, 2011 Jan.
  • Falcon MFF, Echague CG, Hair PS, Nyalwidhe JO, Cunnion KM. Protease inhibitors decrease IgG shedding from staphylococcus aureus increasing complement activation and phagocytosis efficiency. Journal of Medical Microbiology. 2011 Oct;60(10):1415-22.
  • Gronemus JQ, Hair PS, Crawford KB, Nyalwidhe JO, Cunnion KM, Krishna NK. Potent inhibition of the classical pathway of complement by a novel C1q-binding peptide derived from the human astrovirus coat protein. Molecular Immunology. 48(1-3):305-13, 2010 Nov-Dec.
  • ¬†Hair PS, Echague CG, Sholl AM, Watkins JA, Geoghegan JA, Foster TJ, Cunnion KM. Clumping factor A interaction with complement factor I increases C3b cleavage on the bacterial surface of staphylococcus aureus, and decreases complement-mediated phagocytosis. Infection and Immunity. 78(4):1717-1727, 2010 Apr.
  • Hair PS, Gronemus JQ, Crawford KB, Salvi VP, Cunnion KM, Thielens NM, Arlaud GJ, Rawal N, Krishna NK. Human astrovirus coat protein binds C1q and MBL and inhibits the classical and lectin pathways of complement activation. Molecular Immunology. 47(4):792-8, 2010 Jan.
  • Bonaparte RS, Hair PS, Banthia D, Marshall DM, Cunnion KM, Krishna NK. Human astrovirus coat protein inhibits serum complement activation via C1, the first component of the classical pathway. Journal of Virology. 82(2): 817-827, 2008 Jan.
  • Hair PS, Ward MD, Semmes OJ, Foster TJ, Cunnion KM. Staphylococcus aureus clumping factor A binds complement regulator factor I and increases factor I cleavage of C3b. Journal of Infectious Diseases. 198(1):125-33, 2008 Jul.

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