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Translocations

Translocations

What are translocations?

The term translocation is used when the location of specific chromosome material changes. There are two main types of translocations: reciprocal and Robertsonian. In a reciprocal translocation, two different chromosomes have exchanged segments with each other:

Genetic illustration demonstrating reciprocal translocation
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In a Robertsonian translocation, an entire chromosome attaches to another at the centromere. The centromere is the center part of a chromosome that appears "pinched" between the p and q arms:

Genetic illustration demonstrating Robertsonian translocation
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This newly formed chromosome is called the translocation chromosome. The translocation in this example is between chromosomes #14 and 21. When a baby is born with this type of translocation chromosome (between #14 and 21), in addition to one normal 14 and two normal 21 chromosomes, the baby will have Down syndrome. This is also called translocation Down syndrome.

Reviewed Date: 06-23-2013

Translocaciones

Disclaimer: This information is not intended to substitute or replace the professional medical advice you receive from your child's physician. The content provided on this page is for informational purposes only, and was not designed to diagnose or treat a health problem or disease. Please consult your child's physician with any questions or concerns you may have regarding a medical condition.