Jump to:  A   |   B   |   C   |   D   |   E   |   F   |   G   |   H   |   I   |   J   |   K   |   L   |   M   |   N   |   O   |   P   |   Q   |   R   |   S   |   T   |   U   |   V   |   W   |   X   |   Y

Common Childhood Vaccine Won't Worsen Juvenile Arthritis: Study

TUESDAY, June 18 (HealthDay News) -- Measles-mumps-rubella (MMR) booster vaccinations do not appear to worsen disease activity in children with juvenile arthritis, according to a new Dutch study.

"The safety of MMR vaccination has been questioned because disease flares have been described after MMR vaccination," wrote Dr. Marloes Heijstek, of the University Medical Center Utrecht in the Netherlands, and colleagues. "Our trial does not show an effect of vaccination on [juvenile arthritis] activity."

The study included 137 juvenile arthritis patients, aged 4 to 9, who had received primary MMR vaccinations and were randomly assigned either to receive an MMR booster shot or not receive a booster. During follow-up, juvenile arthritis disease activity was about the same for both groups, according to the study, which was published in the June 19 issue of the Journal of the American Medical Association.

The average number of disease flares per patient was 0.44 in the booster shot group and 0.34 in the non-booster group, and both groups had a similar percentage of patients with one or more flares.

Juvenile arthritis is the most common childhood rheumatic disease, and affects between 16 and 150 children per 100,000. Patients with juvenile arthritis are at increased risk for infections due to weakened immune systems caused by the disease or its treatment. Preventing infections in these patients requires safe and effective vaccinations that do not increase disease activity, the researchers noted in a journal news release.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about juvenile arthritis.

SOURCE: Journal of the American Medical Association, news release, June 18, 2013

Reviewed Date: --

Find a pediatrician
Infectious Diseases
Kenji Cunnion, MD
Randall Fisher, MD
Laura Sass, MD
Childrens Orthopedics and Sports Medicine
J. Marc Cardelia, MD
Allison Crepeau, MD
Cara Novick, MD
H. Sheldon St. Clair, MD
Carl St. Remy, MD
Allison Tenfelde, MD
Rheumatology
Christos Gabriel, MD
Matthew Hollander, MD
Health Tips
Growing Up Short or Heavy Can Be Difficult
Helping Children Conquer Fear
How Old Is 'Old Enough' for Contacts?
How to Prevent Childhood Obesity
Kids' Health Concerns Ease with Age
What Kids Drink Is Important, Too
When Your Child Says, 'I'm Sick'
Why Measles Remains a Threat
Quizzes
Immunization Quiz
NewsLetters
People with Diabetes Often Have Arthritis, Too
Diseases & Conditions
AIDS/HIV in Children
Anatomy of a Child's Brain
Anatomy of the Endocrine System in Children
Anxiety Disorders in Children
Asthma and Children
Asthma in Children Index
Bicycle, In-Line Skating, Skateboarding Safety--Injury Statistics and Incidence Rates
Bipolar Disorder in Children
Bone Marrow Transplantation in Children
Brain Tumors in Children
Chemotherapy for Children: Side Effects
Children Living with a Rheumatic Disease
Diagnosing Arthritis and Other Rheumatic Diseases in Children
Diphtheria in Children
During an Asthma Attack
Ewing Sarcoma
Firearms
Hepatitis B (HBV) in Children
Inflammatory and Infectious Musculoskeletal Disorders
Inflammatory and Infectious Neurological Disorders
Inguinal Hernia in Children
Insect Bites and Children
Kidney Transplantation in Children
Measles, Mumps, and Rubella (MMR)
Meningitis in Children
Mood Disorders in Children and Adolescents
Mumps
Muscular Dystrophy
Myasthenia Gravis in Children
Osteosarcoma in Children
Pediatric Arthritis and Other Rheumatic Diseases Statistics
Pediatric Blood Disorders
Poliomyelitis (Polio) in Children
Post-Traumatic Stress Disorder in Children
Preparing the School-Aged Child for Surgery
Rubeola (Measles)
Schizophrenia in Children
School-Aged Child Nutrition
Slipped Capital Femoral Epiphysis
Sports Safety for Children
Superficial Injuries Overview
Television and Children
Thalassemia
The Growing Child: 2-Year-Olds
The Heart
The Kidneys
Treatment for Arthritis and Other Rheumatic Diseases in Children
Vision Overview
Whooping Cough (Pertussis)

Disclaimer: This information is not intended to substitute or replace the professional medical advice you receive from your child's physician. The content provided on this page is for informational purposes only, and was not designed to diagnose or treat a health problem or disease. Please consult your child's physician with any questions or concerns you may have regarding a medical condition.